NanoPAT Process Analytical Technologies
for Industrial Nanoparticle Production
LEARN MORE Online real-time characterisation solutions for
nanoparticle production processes











Photon Density Wave Spectroscopy

An inline process analytical technology capable of calibration-free quantification of light absorption and light scattering in highly turbid, highly concentrated liquid dispersions.


OptoFluidic Force Induction

An active, single particle based high throughput PAT based on induced photonic & microfluidic forces. It provides statistically relevant data streams for particles from 20 nm up to several microns.



A flexible optical technique for monitoring the evolution of suspending particles which size ranges from approx. 100 nm up to few microns.

About the project

While bulk materials have constant physical properties independent of their size, the physical and chemical properties of a nanoparticle are dictated by its size. Accurate characterisation of mean size, size distribution and shape is key to the efficient manufacturing of high-quality nanomaterials. The EU-funded NanoPAT project plans to use three new real-time analytical tools that overcome problems and limitations of conventional characterisation technologies. The new process analytical technologies (PAT) will be Photon Density Wave spectroscopy (PDW), Optofluidic Force Induction (OF2i) and Turbidity Spectrometry (TUS). The innovative technologies will be combined with new data analysis methods to provide, for the first time, real-time analysis of particles on the nanometre scale with sub-minute temporal resolution.

Our partners' expectations:

Our objectives

Nano-scaled materials are abundant in different stages of industrial manufacturing. Physical and chemical properties of these materials are strongly dependent on their size. Characterisation of mean size, size distribution, and shape of nano-scaled particles is very critical for the quality and efficiency of manufacturing processes. Yet, conventional characterisation technologies still show manifold shortcomings which represent a major innovation obstacle for manufacturers of nanoparticles.

The NanoPAT consortium aims at closing this gap by the demonstration of 3 novel, real-time nano-characterisation Process Analytical Technologies (PAT), including real-time data handling for digital process monitoring and product quality control. Those will be validated in 5 different industrial ceramic, polymer and mineral nanoparticles manufacturing and converting environments. This implies that innovating PATs will be paired with new data-analytical technologies in order to provide, for the first time, a real-time analysis for manufacturing processes of particles in the nanometer scale with sub minute temporal resolution.


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